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Complete Information On Anal Cancer With Treatment And Prevention By John Smith Anal cancer is a uncommon form of cancer that occurs in the anus. There are a lot of other risk factors for Anal cancer. Anus is the opening at the end of the rectum around which body waste passes. Perianal is the skin around the outside of the anus. Tumors in this area are skin tumors, not anal cancer. Cancer in the outer part of the anus is more likely to occur in men, cancer of the inner part of the rec